In 1995, Mary Kay Inc. became the first cosmetics manufacturer to be awarded the Star Work Site Designation in OSHA's Voluntary Protection Program (VPP) for its excellent safety record, safety programs and employee involvement. In 1998, 2003 and 2008, Mary Kay Inc. was again recognized for its exemplary safety program and awarded recertification as a Star Work Site.

In the United States, Mary Kay Inc. is a Food and Drug Administration (FDA) registered drug manufacturing operation. This allows the Company to manufacture and distribute certain products classified as over-the-counter drugs, such as sunscreens and acne treatment products. The research team keeps abreast of each country's various government regulatory agencies to ensure that products comply with regulatory restrictions and guidelines.

In 2005, Mary Kay Inc. gave a $1 million endowment to support dermatology research at the University of Texas Southwestern Medical Center in Dallas to help stimulate groundbreaking research and help further advancements in the field of dermatology.

All Mary Kay® sunscreen products carry the prestigious Seal of Recommendation from the Skin Cancer Foundation. This means these products have met stringent criteria for safety and effectiveness.

The Mary Kay® TimeWise® Miracle Set® and the TimeWise Repair® Set carry the trusted Good Housekeeping Seal. This means that the Good Housekeeping Research Institute stands behind the quality, safety, and performance of any product that carries this seal.

Mary Kay has been granted the Personal Care Products Council (PCPC) Consumer Commitment Code. This code goes beyond the requirements of the law and highlights the proactive and responsible approach to product safety supported by cosmetic companies.